Chicago White Sox vs Cleveland Guardians Prediction, Picks and Head-to-Head

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Our Picks in This Matchup

Every breakdown we have published between these two teams, graded against the final score.
Side Picks
4-4 · 50%
Total Picks
4-4 · 50%
Sat, Oct 10 · CHW 0, CLE 2
L Chicago White Sox MLL Over 7
›
Thu, Oct 8 · CHW 5, CLE 9
W Cleveland Guardians MLL Under 7.5
›
Wed, Oct 7 · CHW 3, CLE 9
L Chicago White Sox MLW Over 7.5
›
Mon, Oct 5 · CHW 4, CLE 3
W Chicago White Sox MLW Over 6.5
›
Sat, Oct 3 · CHW 3, CLE 0
L Cleveland Guardians MLW Under 7
›
Wed, Sep 16 · CHW 3, CLE 6
W Cleveland Guardians MLL Under 7.5
›
Tue, Sep 15 · CHW 6, CLE 7
L Chicago White Sox MLW Over 8.5
›
Mon, Sep 14 · CHW 7, CLE 3
W Chicago White Sox MLL Under 7
›

Head to Head

Every meeting this season and last.
White Sox wins
11
Guardians wins
20
Cleveland Guardians
Guardians won 2-0
Sat, Oct 10 · at Guardians · Playoffs
Cleveland Guardians
Guardians won 9-5
Thu, Oct 8 · at White Sox · Playoffs
Cleveland Guardians
Guardians won 9-3
Wed, Oct 7 · at White Sox · Playoffs
Chicago White Sox
White Sox won 4-3
Mon, Oct 5 · at Guardians · Playoffs
Chicago White Sox
White Sox won 3-0
Sat, Oct 3 · at Guardians · Playoffs
Cleveland Guardians
Guardians won 6-3
Wed, Sep 16 · at Guardians
Cleveland Guardians
Guardians won 7-6
Tue, Sep 15 · at Guardians
Chicago White Sox
White Sox won 7-3
Mon, Sep 14 · at Guardians
Chicago White Sox
White Sox won 5-3
Sun, Aug 9 · at White Sox
Chicago White Sox
White Sox won 6-3
Sat, Aug 8 · at White Sox
Cleveland Guardians
Guardians won 8-2
Fri, Aug 7 · at White Sox
Chicago White Sox
White Sox won 7-6
Sun, Jul 5 · at Guardians
Chicago White Sox
White Sox won 3-1
Sat, Jul 4 · at Guardians
Cleveland Guardians
Guardians won 4-3
Fri, Jul 3 · at Guardians
Cleveland Guardians
Guardians won 6-5
Thu, Jul 2 · at Guardians
Cleveland Guardians
Guardians won 4-3
Wed, Jun 24 · at White Sox
Chicago White Sox
White Sox won 2-1
Tue, Jun 23 · at White Sox
Chicago White Sox
White Sox won 6-5
Mon, Jun 22 · at White Sox
Cleveland Guardians
Guardians won 3-2
Sun, Sep 14 · at Guardians
Cleveland Guardians
Guardians won 3-1
Sat, Sep 13 · at Guardians
Cleveland Guardians
Guardians won 4-0
Fri, Sep 12 · at Guardians
Chicago White Sox
White Sox won 6-4
Sun, Aug 10 · at White Sox
Cleveland Guardians
Guardians won 3-1
Sat, Aug 9 · at White Sox
Cleveland Guardians
Guardians won 9-5
Fri, Aug 8 · at White Sox
Cleveland Guardians
Guardians won 6-5
Sun, Jul 13 · at White Sox
Cleveland Guardians
Guardians won 6-2
Sat, Jul 12 · at White Sox
Cleveland Guardians
Guardians won 4-2
Fri, Jul 11 · at White Sox
Chicago White Sox
White Sox won 5-4
Fri, Jul 11 · at White Sox
Cleveland Guardians
Guardians won 6-1
Thu, Apr 10 · at Guardians
Cleveland Guardians
Guardians won 3-2
Wed, Apr 9 · at Guardians
Cleveland Guardians
Guardians won 1-0
Tue, Apr 8 · at Guardians

Team Comparison

2026 season.
White SoxGuardians
84-78Record85-77
48-33Home41-40
36-45Road44-37
7-3Last 108-2
W1StreakL1
Season stats, league rank in brackets. Longer bar, stronger league standing.
4.8 (5th)
Runs
(24th) 4.2
(League Avg: 4.5 Runs/Game)
0.726 (9th)
OPS
(26th) 0.696
(League Avg: 0.719 OPS)
32.0% (9th)
OBP
(17th) 31.6%
(League Avg: 31.8%)
0.406 (8th)
SLG
(27th) 0.380
(League Avg: 0.400 SLG)
211 (5th)
HR
(27th) 162
(League Avg: 186 HR)
7.9 (25th)
Hits
(22nd) 8.0
(League Avg: 8.2 Hits/Game)
23.6% (25th)
AVG
(22nd) 23.9%
(League Avg: 24.4%)
93 (18th)
SB
(7th) 146
(League Avg: 110 SB)
4.4 (13th)
Runs Allowed
(8th) 4.1
(League Avg: 4.5 Runs/Game)
4.12 (14th)
ERA
(8th) 3.77
(League Avg: 4.17 ERA)
1.31 (19th)
WHIP
(8th) 1.26
(League Avg: 1.30 WHIP)
8.35 (17th)
K/9
(3rd) 9.58
(League Avg: 8.50 K/9)
180 (14th)
HR Allowed
(13th) 175
(League Avg: 186 HR)
8.1 (14th)
Hits Allowed
(10th) 8.0
(League Avg: 8.2 Hits/Game)
24.3% (16th)
BAA
(11th) 23.8%
(League Avg: 24.4%)
98.6% (13th)
FLD%
(17th) 98.5%
(League Avg: 98.6%)
This information is for entertainment purposes only and is not any form of financial or gambling advice. Sports involve high variance therefore always be responsible and manage your risk accordingly.
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